Berberis aquifolium, Berberis aristata, Argemone mexicana, Berberine
Berberine, or Barberis aristata, is a widespread alkaloid in traditional Chinese medicine. Its source is in the extraction of various plants used in traditional Chinese medicine. Its main benefit is reducing insulin resistance and improving biomarkers of type II diabetes, such as fasting glucose and glycosylated hemoglobin.
- Origen: Plant Based
- Fuente: Itself
- Tipo: Alkaloid Chemical Compound
- Rango de edad: Adults (18-60), Seniors (>60)
- Toxicidad: May be toxic in high doses
- Outcomes: Diabetes y Glucemia, Control del Azúcar en La Sangre
What are Berberine benefits?
Barberine is a plant-based substance that is considered herbal and is widely used in traditional Chinese medicine. Its major benefits are breaking down blood sugar, helping with insulin resistance. In addition, it reduces sugar production in the liver and improves hormone function. A great ally in the treatment of diabetes, it also acts on blood pressure and wound healing, and protects the brain from degenerative diseases. Because it is extracted from plants, there are no food sources with this alkaloid, so check out our quiz to find out if this nutraceutical fits your needs!
Table of relations
Published articles about Berberine and Control del Azúcar en La Sangre
6 months of treatment with 2g inositol to women with hirsutism was associated with reductions in the symptoms directly as well as improvements in insulin sensitivity.
La terapia combinada con mio-inositol y D-chiro-inositol reduce el riesgo de enfermedad metabólica en pacientes con sobrepeso de PCO en comparación con la suplementación con mio-inositol solo
Supplementation of myo-inositol by itself at 2g daily for a period of six months in women with PCOS was associated with improvements in diastolic blood pressure. The combination with D-chiroinositol was the same at a lower dose (550mg and 13.8mg, respectively) when measured at six months, but seemed to act faster as inositol at 2g required six months to be fully effective.
Efectos de inositol en función ovárica y factores metabólicos en mujeres con PCOS: un ensayo aleatorizado con placebo con placebo doble
200mg of inositol daily (in two divided doses of 100mg) for a period of 12 weeks in women with PCOS was ineffective in improving the glucose metabolic markers yet was effective in reducing body weight and improving fertility.
Efectos metabólicos y hormonales de mio-inositol en mujeres con síndrome de ovario poliquístico: un ensayo doble ciego
Supplementation of 4,000mg inositol daily for a period of 12-16 weeks in women with PCOS was able to improve tolerance to glucose and glucose handling (as well as reduce the amount of insulin secreted in response to a meal) with minor benefits to cardiovascular health as well.
Efectos de un año de la suplementación con mio-inositol en mujeres posmenopáusicas con síndrome metabólico.
Supplementation of myo-inositol at 2g twice daily for the course of one year in postmenopausal women with metabolic syndrome was associated with improvements on all metabolic parameters measured (cardiovascular health and glucose metabolism) although no influence on weight was noted.
La administración de inositol reduce el estrés oxidativo en los eritrocitos de pacientes con síndrome de ovario poliquístico
Supplementation of 1,200mg Myo-inositol daily for a period of 12 weeks in normal weight women (22-30yrs) with PCOS was able to decrease weight (−1.83+/-1.86kg, very unreliable in magnitude) and improved markers of glucose and androgen metabolism. An improvement in oxidative biomarkers was also noted (GSH in red blood cells).
Ensayo aleatorizado, doble ciego controlado con placebo: efectos del mio-inositol sobre la función ovárica y los factores metabólicos en mujeres con PCOS
4g of inositol daily for a period of 16 weeks in women with PCOS was ineffective in improving parameters of insulin sensitivity while it was sufficient to improve biomarkers of steroid metabolism and fertility. Weight was decreased in all subjects who were not morbidly obese.
Respuesta diferencial de insulina a la administración de mio-inositol en pacientes con síndrome de ovario poliquístico obeso
Supplementation of 2,000mg inositol (INOFERT) once daily for eight weeks in obese women with PCOS was able to improve insulin sensitivity and other biomarkers of glucose metabolism only in those with higher circulating insulin concentrations. No placebo control was used in this study.
El tratamiento con mio-inositol aumenta los plasmalógenos séricos y disminuye un pequeño LDL denso, particularmente en sujetos hiperlipídicos con síndrome metabólico
Two weeks supplementation of _myo_-inositol at 5g (first week) and 10g (second week) was able to increase circulating levels of choline plasmalogen, which is thought to be the reason behind a reduction in LDL-C. These changes were not present in persons without metabolic syndrome.
5g psyllium taken thrice a day for 6 weeks was able to significantly reduce glucose and all improve all parameters of a lipid panel in diabetic persons relative to placebo; treatment was well tolerated.
Supplementation of 14g of psyllium fiber daily for six weeks was associated with a significantly reduced absorption of glucose (12.2%) and a reduction in other parameters of glucose metabolism including insulin (5%), HbA1c (3.8%), 24-hour urinary glucose (22.5%), fructosamine (), and uric acid (10.9%). Some improvements were also noted in the lipid profile.
Los efectos reductores de colesterol de los cereales de fibra soluble como parte de una dieta prudente para pacientes con hipercolesterolemia leve a moderada
Supplementation of 10g psyllium husk via cereal in persons with high cholesterol for 6 weeks failed to influence hematological parameters and body weight while reducing total cholesterol and LDL-C.
Efectos de la fibra dietética y la dieta de índice glucémico bajo en el control de la glucosa en sujetos con diabetes mellitus tipo 2
Assessment of 7 trials using psyllium supplement and/or a low glycemic diet for diabetes management concluded that psyllium was possibly useful as an adjuvant treatment for blood glucose and HbA1c in diabetics on drugs who may require further therapy to reduce glucose.
In diabetic patients, Berberine at 0.5-1.5g daily for an average period of 12 weeks was associated with minor to moderate improvements on all measured glucose and lipid parameters; rivalling oral hypoglycemics in potency.
Tratamiento de la diabetes tipo 2 y la dislipidemia de tipo 2 con la planta de cerberina alcaloide natural.
Berberine in isolation at 1g for 3 months was able to reduce triglycerides and fasting glucose levels in type II diabetics. Total cholesterol and LDL also decreased, and an increase in glucose disposal rate was seen. Insulin sensitivity showed a trend for improvement, but did not reach statistical significance.
184 patients with nonalcoholic fatty liver disease were randomized to one of three arms for 16 weeks: lifestyle intervention alone, lifestyle interventions plus 15mg pioglitazone daily, or lifestyle interventions plus 0.5g berberine three times a day. Berberine plus lifestyle changes significantly improved liver fat content, BMI, HOMA-IR, total cholesterol, and triglycerides significantly more than lifestyle interventions alone. The berberine group tended to have minor digestive issues that tended to resolve 2 weeks into the study.
Efecto de la administración berberina sobre el síndrome metabólico, la sensibilidad a la insulina y la secreción de insulina.
24 people with metabolic syndrome were randomized to placebo or 0.5g berberine three times a day for three months. Decrease in waist circumference in females only, systolic blood pressure, triglycerides, area under the curve of glucose and insulin, and Matsuda index were all seen to be significant in the berberine group versus placebo.
La suplementación con biotina reduce el plasma triacylglicerol y VLDL en pacientes diabéticos tipo 2 y en sujetos no diabéticos con hipertrigliceridemia
Supplementation of 15mg biotin in subjects with high triglycerides, with or without type II diabetes, appeared to reduce serum triglycerides and vLDL over the course of 28 days therapy. There were no other biochemical changes noted, and while there was a trend to reduce BMI it did not reach significance.
Supplementation of chromium to type II diabetics for 28 weeks noted a reduction in blood glucose relative to baseline and placebo, and the minor changes in HbA1c and insulin turned out to be significant due to an increase seen in placebo. Weight and blood pressure were not significantly different, nor were any parameter of lipid metabolism measured.
Los efectos del cromo inorgánico y la suplementación con levadura de cervecería sobre tolerancia a la glucosa, lípidos séricos y dosis de fármacos en individuos con diabetes tipo 2.
Low dose chromium supplementation (23.3mcg) via Brewer's Yeast and 200mcg chromium as trichloride for eight weeks in type II diabetics both appeared to reduce both fasting and postprandial blood glucose (75g glucose tolerance test) and was able to reduce fructosamine as well.
La influencia de la leche que contiene cloruro de cromo al control glucémico de los pacientes con diabetes mellitus tipo 2: un ensayo aleatorizado, doble ciego, controlado con placebo
The addition of 200mcg chromium (as chloride) to milk powder, relative to a milk powder placebo, in type II diabetics already on medication (gliclazide) noted that there was a reduction in blood glucose, insulin, and improvement in insulin sensitivity over the course of 16 weeks in men only. Acute insulin response following an oral glucose tolerance test (10 minutes after) was unaffected in both sexes.
La ingesta elevada de cromo suplementario mejora las variables de glucosa y insulina en individuos con diabetes tipo 2
4 months supplementation of 200mcg or 1,000mcg chromium (as picolinate) in type II diabetics was able to reduce fasting and postprandial blood glucose (higher dose only), fasting and postprandial insulin (both groups equally), HbA1c (higher dose only), and total cholesterol (higher dose only) with no influence on HDL nor body weight.
In overweight women reporting intense carbohydrate cravings at least twice a week, supplementation of 1,000mcg chromium appeared to reduce hunger and cravings over the course of weight weeks which resulted in a greater reduction in overall food intake (25%) than did placebo (8%). This reduction in food intake led to weight loss, but was independent of any changes in glucose metabolism.
Un ensayo piloto aleatorizado de doble ciego de picolinato de cromo para el trastorno de la alimentación excesiva: los resultados del estudio de la alimentación y el cromo de los binges (playa)
Six months supplementation of chromium as picolinate (600µg or 1000µg) was able to nonsignificantly reduce symptoms of binge eating disorder (binge frequency) and weight relative to placebo, while HbA1c and blood glucose also failed to reach statistically significant reductions despite trends to do so.
Efectos de la suplementación con cromo a corto plazo sobre la sensibilidad a la insulina y la composición corporal en niños con sobrepeso: estudio aleatorizado, doble ciego, controlado con placebo
400mcg chromium given to overweight children who were also given exercise and diet plans (relative to diet and exercise paired with placebo) over the course of six weeks failed to reduce bodyweight relative to placebo (at the P level of 0.05) but the reduction in fat mass and increase in lean mass was greater with chromium than with placebo. Insulin sensitivity was improved to a statistically significant degree, but no other health variable was beneficially influenced.
Efecto del entrenamiento de la resistencia con o sin suplementos de picolinato de cromo en el metabolismo de la glucosa en hombres y mujeres mayores.
In otherwise healthy but overweight aged adults, the combination of chromium plus resistance training (relative to placebo and training) over 13 week dosed at 1,000mcg failed to augment the benefits of exercise (in reducing insulin AUC following an oral glucose tolerance test) and did not exert any hypoglycemic actions.
Influencia de la levadura enriquecida con cromo sobre la glucosa en la sangre y las variables de insulina, los lípidos de la sangre y los marcadores de estrés oxidativo en sujetos con diabetes mellitus tipo 2
In obese type II diabetic (on medication) subjects given supplemental chromium via yeast (400 micrograms daily) for 12 weeks was associated with a decrease in blood glucose relative to placebo but all other measured biomarkers were unchanged, although a reduction in insulin and weight in both groups tended to decrease further with chromium. Lipid peroxidation (MDA) was unaffected and the antioxidant enzymes were mostly unaffected, although a decrease in glutathoine and glutathione peroxidase seen at the end of the trial in placebo was mitigated with chromium.
La suplementación con cromo acorta la duración del intervalo QTC en pacientes con diabetes mellitus tipo 2
Supplementation of 1,000mcg chromium daily for three months in type II diabetics was able to shorten QTc intervals, suggesting a cardioprotective effect (as prolonged QTc intervals are indicative of cardiovascular mortality). Aside from insulin (which was also reduced), no other parameter was influenced.
Efectos antioxidantes y resistencia a la insulina Mejora del cromo combinado con la suplementación con vitamina C y E para la diabetes mellitus tipo 2
In type II diabetics with an HbA1c over 8.5% given 1mg of chromium via yeast, supplementation was associated with a reduction in blood glucose (11%) and HbA1c (0.7%, from 10.2% to 9.5%) alongside an increase in insulin sensitivity. Lipid peroxidation, as assessed by TBARS, was also reduced with chromium by 18.7%. An increase in glutathoine peroxidase was noted, but catalase and SOD were unaffected.
Efecto de la suplementación con el picolinato de cromo en los títulos de anticuerpos a 5-hidroximetil uracilo
In 11 middle aged obese women given 400mcg chromium (as picolinate) daily for eight weeks, there was no observable change in the anti-HMdU antibody suggesting no DNA damage from supplementation.
Efecto de cromo en glucosa y perfiles lipídicos en pacientes con diabetes tipo 2; Una revisión de metanálisis de los ensayos aleatorios.
A meta-analysis on chromium in type II diabetics where supplementation lasted for over three months noted that, relative to placebo, there was a mild but significant reduction in blood glucose. HbA1c and all biomarkers of lipid metabolism, as well as weight, were all unaffected. This meta-analysis was restricted to type II diabetics and the duration of at least three months, but at times included studies containing chromium enriched yeast and biotin supplementation alongside the chromium.
Caracterización de la respuesta metabólica y fisiológica a la suplementación con cromo en sujetos con diabetes mellitus tipo 2
Supplementation of 1mg chromium (in the form of chromium picolinate) in two divided doses daily for 24 weeks in type II diabetics noted that while there was a trend to increase insulin sensitivity, this was not statistically significant and only 46% of persons were considered responders. No other changes were noted in diet, glucose metabolism, and the response to chromium was more associated with baseline insulin resistance rather than the kinetics of chromium after ingestion.
La suplementación con cromo no mejora la tolerancia a la glucosa, la sensibilidad a la insulina o el perfil lipídico: un ensayo de suplementación de doble ciego aleatorizado, controlado con placebo, controlado con placebo en los sujetos con tolerancia a la glucosa con discapacidad
Supplementation of 400mcg chromium (as picolinate) twice daily in obese participants with impaired glucose tolerance failed to exert any appreciable benefit relative to placebo over the course of three months.
Efectos de la suplementación aguda del cromo en el metabolismo postprandial en hombres jóvenes sanos
The addition of 400 or 800μg chromium (as picolinate) to a test meal containing 75g carbohydrate from breads noted that there was no significant influence on postprandial metabolism when assessing the whole group, but the subjects could be divided into responders and nonresponders where said responders reduced the glucose AUC by 30-36% (lower dose being more effective). Insulin was not affected in any person, and the nonresponders appeared to have a more meat and milk based diet than a plant based one. Nonresponders also had a significantly higher iron and transferrin content in the blood (transferrin saturation and ferritin content similar).
Los efectos de la levadura de cromo y cervecería inorgánica sobre tolerancia a la glucosa, lípidos plasmáticos y cromo plasmático en sujetos ancianos
In otherwise healthy free living adults, supplementation of chromium either as trichloride (200mcg chromium) or as yeast (5g yeast containing 10.8mcg chromium) failed to significantly influence any measured parameter in the blood despite an increase of chromium in the blood from trichloride including glucose tolerance to an oral glucose tolerance test.
Efectos beneficiosos de la suplementación de picolinato de cromo oral sobre control glucémico en pacientes con diabetes tipo 2: un estudio clínico aleatorio
In older adults with evidence of memory decline, 1,000mcg chromium (as picolinate) daily for 12 weeks failed to influence glucose metabolism and did not influence depressive symptoms. Despite no influence on memory over the 12 weeks, there appeared to be significantly less inclusion errors during testing and increased activity in some regions of the right half of the brain during memory testing.
Supplementation of 1mg chromium as picolinate in obese adults over the course of 24 weeks failed to influence body weight either alone or in combination with nutritional education (teaching participants to eat better) and no other parameter in the blood or via CT scans was modified with supplementation.
Efectos de cromo sobre la tolerancia a la glucosa y la sensibilidad a la insulina en personas en riesgo de diabetes mellitus
Supplementation of chromium picolinate at 500mcg or 1,000mcg for six months in persons at risk for type II diabetes has failed to influence any biomarkers of glucose metabolism and was said to not confer any protection against the development of type II diabetes.
Efectos de la suplementación con cromo sobre la síntesis de glicógenos después del ejercicio de alta intensidad
Supplementation of 600mcg chromium daily for a month failed to significantly modify glycogen depletion, concentrations, or resynthesis rates surrounding exercise in untrained or minorly trained men relative to placebo. Lactate AUC was higher with chromium intake relative to placebo.
Efectos de la ingesta de carbohidratos y cromo durante el ejercicio intermitente de alta intensidad para la fatiga
In otherwise active men given a carbohydrate drink with or without an additional 400mcg chromium (as picolinate) subject to a shuttle run test an hour after the drink, the addition of chromium failed to significantly alter any change that carbohydrate was able to induce relative to water control suggesting no additional benefit.
El tratamiento con cromo no tiene efecto en los pacientes con diabetes tipo 2 en una población occidental: un ensayo aleatorizado, doble ciego y controlado con placebo
Six months supplementation of chromium at 400mcg via enriched yeast to type II diabetics already on medications failed to confer any additional benefits, particularly the primary outcome (to see if a 0.5% reduction in HbA1c was reached).
La suplementación con picolinato de cromo atenúa el aumento del peso corporal y aumenta la sensibilidad a la insulina en sujetos con diabetes tipo 2
Supplementation of 1,000µg chromium (as picolinate) alongside sulfonylurea therapy for 10 months in type II diabetic persons noted that, relative to a sulfonylurea/placebo pairing, that chromium resulted in an additional decrease in glucose and free fatty acids in serum without any other significant alterations. There appeared to be an anti-obese effect of chromium, as the 0.9kg weight gain with sulfonylurea therapy was mitigated with chromium coingestion.
Efecto beneficioso de la suplementación con cromo sobre glucosa, HbA1C y variables lipídicas en individuos con diabetes tipo 2 de nueva aparición.
Supplementation of brewers yeast (conferring 42 μg chromium) in newly diagnosed diabetics for three months was able to significantly reduce blood glucose (47.6%), HbA1c (from 9.5% to 6.8%), and systolic blood pressure (12%) while causing some benefit to all lipid parameters except vLDL and HDL relative to placebo.
Chromium Picolinate no mejora las características clave del síndrome metabólico en adultos no diabéticos obesos
Chromium supplementation at 1,000mcg daily (as picolinate) increased the acute insulin response to glucose but failed to influence any other measured parameter of metabolic syndrome after 16 weeks supplementation in adults with signs of metabolic syndrome yet no diagnosed diabetes.
Efectos de la suplementación con levadura de cromo Brewer en masa corporal, carbohidratos de sangre y lípidos y minerales en pacientes diabéticos tipo 2
In obese type II diabetic subjects given trivalent chromium supplementation via Brewer's Yeast (500mcg chromium) for eight weeks, supplementation was able to exert a minor hypoglycemic effect which failed to reach statistical significance (P=0.08) while trends on other biochemical parameters failed to reach statistical significance.
En pacientes con infección por VIH, la suplementación con cromo mejora la resistencia a la insulina y otras anomalías metabólicas: un ensayo aleatorizado, doble ciego y controlado con placebo
Supplementation of 400mcg chromium (as nicotinate) daily for 16 weeks in persons with HIV who were insulin resistant due to antiretroviral therapy appeared to improve insulin sensitivity and some other measured parameters such as triglycerides and weight when used as adjuvant.
Impacto de la cocina y la digestión, in vitro, sobre la capacidad antioxidante y la actividad antiinflamatoria de la canela, el clavo y la nuez moscada.
Efectos antibacterianos de la canela: desde la granja a la alimentación, la cosmética y las industrias farmacéuticas.
Eficacia de la canela para reducir la hemoglobina A1C en pacientes con diabetes tipo 2: un ensayo aleatorizado y controlado
Efecto de la canela sobre glucosa y niveles de lípidos en diabetes tipo 2 dependiente de la insulina.
Efecto de la canela en la glucosa en sangre postprandial, el vaciamiento gástrico y la saciedad en sujetos sanos.
Efecto de la canela molida en la concentración postprandial de glucosa en sangre en peso normal y adultos obesos
El producto final de glicación avanzado, NEPSILON- (carboximetil) lisina, es un producto de la peroxidación lipídica y las reacciones de glicójecaguas.
Carboxymetil Lysine, un producto final avanzado de glicación, y diabetes incidentes: un análisis de casos-cohorte del estudio ARIC
La investigación de los parámetros oxidativos relacionados con el estrés en la diabetes mellitus tipo 2
Efectos de la suplementación aguda de Panax Ginseng en la resistencia corriendo en un HOT & AMP; Ambiente húmedo
200mg of Panax Ginseng, taken acutely one hour before endurance testing, was unable to increase physical performance in runners. Lactate production was reduced when measured 60 minutes after the start of exercise.
Ginseng rojo coreano (Panax Ginseng C.A.A. Meyer) Fracciones de la raíz: efectos diferenciales en la glucemia postprandial en individuos sanos
Korean Red Ginseng, given in a cross-over manner to 13 persons over 3 visits to the lab, in either 3g of the ginseng body or 3g of the ginseng rootlets. Ginseng was found to reduce post-prandial glucose when administered as the body, but the rootlets with a higher ginsengoside content were unable to do so.
In type II diabetics given Panax Ginseng at 100-200mg for a period of 8 weeks, improvements in body weight, mood, and glycemic profiles were seen.
Efectos del ginseng rojo coreano en los riesgos cardiovasculares en sujetos con síndrome metabólico: un estudio controlado aleatorio doble ciego
12 weeks of 4.5g KRG supplementation in persons with metabolic syndrome noted an increase in HDL-C, but other parameters tested were either not affected or affected to the same extent in placebo
El ginseng y el ginsenósido no mejoran la función de la célula β o la sensibilidad a la insulina en sujetos con sobrepeso y obesos con tolerancia de glucosa con problemas de glucosa o diabetes
3g of ginseng daily for 2 weeks, and then 8g for the next two weeks, in obese diabetic (or pre-diabetic) adults for 30 days was unable to alter fasting glucose and fasting insulin sensitivity, as well as B-cell function. No circulating levels of ginsenosides were seen despite being advised to consume their final dose 30 minutes before testing.
Las dosis únicas de Panax Ginseng (G115) reducen los niveles de glucosa en la sangre y mejoran el rendimiento cognitivo durante la actividad mental sostenida
Cognition as assessed by serial sevens was significantly improved, and blood glucose decreased, after ingestion of 200mg and 400mg G115 extract
64 subjects were divided into placebo or experimental, and the latter given 3g of red ginseng extract for 3 months. Although reductions in blood pressure and improvements in heart health were seen with Ginseng, these were also found in placebo.
Efectos de la suplementación con ginseng de Panax en el daño muscular y la inflamación después de la cinta de correr cuesta arriba corriendo en humanos
Insulin sensitivity was improved and glucose reduced during an Oral Glucose Tolerance Test (OGTT) and muscle damage induced by downhill running was reduced and inflammation production hindered (assessed via IL-6), after consumption of 20g Red Ginseng extract daily in young healthy athletes.
Efectos del ginseng panx, consumido con y sin glucosa, en los niveles de glucosa en la sangre y el rendimiento cognitivo durante las tareas sostenidas 'exigentes mentalmente'
200mg and 400mg of 4% ginsenosides can decreaes blood glucose from around 7-12% in otherwise healthy persons within 60-120 minutes after ingestion, as well as increase cognitive function as assessed by serial sevens subtraction; the two do not seem related.
Panax Ginseng no tiene ningún efecto sobre los índices de la regulación de la glucosa después de la ingesta aguda o crónica en voluntarios sanos
Two separate studies by the same research group demonstrated that Panax Ginseng had no effect on HbA1c, fasting insulin, or fasting glucose in healthy volunteers.
17mmol Magnesium Orotate daily for 4 weeks was associated with significant improvement on the time it took to complete triathalon-like testing.
La suplementación oral de magnesio mejora la sensibilidad a la insulina y el control metabólico en los sujetos diabéticos tipo 2: un ensayo aleatorizado de doble ciego controlado
Magnesium chloride, when correcting a deficiency, is associated with improvements in insulin sensitivity, glucose, and HbA1c. 2.5g Magnesium chloride equates to 450mg elemental magnesium
Efectos de la suplementación oral del magnesio sobre la sensibilidad de la insulina y la presión arterial en NORMO-MAGNESEMIC NONiAbético con sobrepeso adultos coreanos
No significant effects were observed in persons with normal magnesium status and without hypertension or pre-diabetes when dosed at 300mg daily
360mg Magnesium daily for 3 months in type II diabetics failed to find any influence on measured parameters.
El magnesio mejora la función de células beta para compensar la variación de la sensibilidad a la insulina: ensayo clínico doble ciego y aleatorizado
Correcting a magnesium deficiency in nondiabetic and normotensive men (0.66mM to 0.78mM) corrects various pancreatic abnormalities and blood pressure, but no significant influence on weight or triglycerides was noted and the increase in HDL-C failed to reach statistical significance after 3 months.
El efecto de la suplementación con magnesio sobre los niveles de glucosa y insulina de los deportistas de Tae-Kwan-Do y sujetos sedentarios
Glucose was increased at rest and post-fatigue in sportsmen given magnesium relative to sportsmen controls, dose was not given, but was used for 4 weeks.
La suplementación oral de magnesio reduce la resistencia a la insulina en sujetos no diabéticos: un ensayo aleatorizado de doble ciego, con placebo controlado con placebo
Pre-diabetic (insulin resistant obese persons) that were not magnesium deficient experienced a reduction in fasting blood glucose after 365mg Magnesium Aspartate-Chloride for 6 months. Serum ionized magnesium increased, but erythrocytic and serum were not significant,.
El efecto de reducir la presión arterial por la suplementación con magnesio en los adultos hipertensos diabéticos con niveles de magnesio séricos bajos: un ensayo clínico aleatorizado, doble ciego, controlado con placebo controlado con placebo.
A very small increase in HDL but significant reductions in blood pressure observed after 450mg supplementation for 4 months in hypertensive adults with diabetes and low magnesium levels
La suplementación con zinc oral no mejora la tensión oxidativa o la función vascular en pacientes con diabetes tipo 2 con niveles normales de zinc
Supplementation of 240mg elemental zinc as gluconate daily for a period of three months in diabetics has failed to provide any additional benefit to circulating biomarkers when the participants were already at adequate zinc stores.
Efecto de la suplementación con zinc sobre marcadores de resistencia a la insulina, estrés oxidativo e inflamación entre los niños prepubescentes con síndrome metabólico
Supplementation of 20mg elemental zinc daily for 8 weeks in obese adolescents who were insulin resistant noted improvements in all biomarkers of glucose metabolism and inflammatory parameters, and a beneficial change was seen in oxidative biomarkers as well as most of the lipid panel (no influence on HDL-C).
Efecto de la suplementación con zinc sobre resistencia a la insulina y componentes del síndrome metabólico en niños obesos prepúberes
In obese children given 20mg elemental zinc supplementation daily for eight weeks, supplementation was associated with a betterment of biomarkers of glucose metabolism although it was not associated with weight loss nor lipid profiles.
Las células del cuerpo usan glucosa para producir energía. La glucosa proviene de los alimentos y se almacena en el cuerpo en forma de glucógeno (en los músculos y el hígado) o glucosa circulante (en la sangre). Las células necesitan la hormona insulina para capturar las moléculas de glucosa. El equilibrio glucosa / insulina en la sangre es esencial para el correcto funcionamiento de todo el metabolismo del cuerpo. Un cambio en este metabolismo puede conducir a disfunciones fisiológicas graves, lo que lleva al desarrollo de enfermedades crónicas no transmisibles, como la diabetes tipo II y las enfermedades cardiovasculares. Existen varias clases de compuestos que influyen en este metabolismo, estos pueden aumentar la síntesis y secreción de insulina, disminuir los niveles de glucosa en sangre, reducir la absorción inmediata de carbohidratos, regular la sensibilidad de las células a la insulina, entre otros.